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SMILE Pro · ReLEx SMILE · Eye treatments

SMILE Pro Eye Surgery in Turkey — Flapless Refractive Surgery at Eyeglow Istanbul

SMILE Pro (Small Incision Lenticule Extraction) on the ZEISS VisuMax 800 platform — a flapless refractive procedure for myopia and astigmatism that preserves corneal biomechanical strength and lowers dry eye risk compared with LASIK. Led by our refractive surgical team. Written quote, complication insurance and one year of structured aftercare.

SMILE Pro laser eye surgery at Eyeglow, Istanbul
Procedure time10–12 min per eye
Laser pulse time~10 seconds (SMILE Pro)
AnaesthesiaTopical drops
Functional vision24–48 hours
Time in Istanbul3–4 nights
Follow-up1 year structured
What it is

What is SMILE eye surgery?

SMILE (Small Incision Lenticule Extraction) is a flapless refractive procedure performed with the ZEISS VisuMax femtosecond laser. The laser creates a precisely shaped disc of corneal tissue (a "lenticule") inside the cornea plus a 2-to-4-millimetre side incision. The surgeon removes the lenticule through the small incision, which permanently changes the corneal curvature and corrects myopia and astigmatism — without lifting a corneal flap.

At Eyeglow Health in Istanbul, SMILE is performed with the ZEISS VisuMax 500 (classic ReLEx SMILE) and VisuMax 800 (SMILE Pro) platforms — the same equipment used in major US and European refractive centres. SMILE was FDA-approved for myopia in September 2016 and for myopic astigmatism in October 2018; more than seven million SMILE procedures have been performed worldwide (ZEISS Meditec global registry). SMILE Pro on VisuMax 800 delivers the laser in approximately 10 seconds per eye and includes automatic cyclorotation compensation for improved astigmatic correction.

SMILE is the appropriate refractive choice for patients with myopia (–1 to –10 D) and astigmatism up to –3 D who want the benefits of laser refractive surgery without a corneal flap — particularly contact-sport athletes, military personnel, eye-rubbers and patients with mild-to-moderate dry eye. It is not suitable for hyperopia, very thin corneas, suspected keratoconus or severe untreated ocular surface disease. That assessment belongs to a surgeon who has personally reviewed your Pentacam, pachymetry and wavefront — not to a marketing brochure.

How it works

From first consultation to recovery at home

  1. 01

    Online consultation

    You share recent prescription history, prior eye exams and any contact-lens intolerance. Our refractive surgical team reviews your case and confirms whether your prescription, corneal thickness and lifestyle make SMILE the right choice over LASIK, PRK or ICL — before a quote is issued.

  2. 02

    Pre-operative imaging in Istanbul

    On day 1 we measure Pentacam Scheimpflug topography, ultrasound or OCT pachymetry, wavefront aberrometry, dry eye and tear film evaluation, and pupil dynamics. SMILE preserves corneal nerves better than LASIK, but pachymetry must still be ≥500 µm in most cases. Soft contact lenses stopped one week before; rigid lenses three weeks before.

  3. 03

    Personalised treatment plan

    Our refractive surgical team reviews your imaging with you and confirms which SMILE protocol (SMILE Pro on VisuMax 800, or classic ReLEx SMILE on VisuMax 500), the expected refractive outcome and the individual risk profile of your eyes before you sign consent.

  4. 04

    The procedure (10–12 minutes per eye)

    Both eyes are typically treated in the same session. The ZEISS VisuMax femtosecond laser creates a precisely shaped corneal lenticule (a thin disc of corneal tissue containing your refractive prescription) inside the cornea, plus a 2–4 mm small access incision at the corneal edge. The surgeon manually separates and removes the lenticule through this small opening — no corneal flap, no excimer ablation. SMILE Pro delivers the laser pulses in roughly 10 seconds per eye on the latest VisuMax 800.

  5. 05

    Day 1 and day 7 reviews

    You return the morning after surgery and again before flying home. Functional vision typically returns within 24 to 48 hours, slightly slower than LASIK in some patients but with a more comfortable first-day experience. No flap means no flap-related restrictions for sports or rubbing — the cornea recovers its biomechanical strength faster than after LASIK.

  6. 06

    One-year structured aftercare

    Scheduled video reviews at one, three, six and twelve months. Your coordinator stays the same throughout. Refractive enhancement (if ever needed, ~3% of cases) is offered as a surface PRK touch-up — included within 12 months at no extra surgical fee.

Compared to LASIK / PRK / ICL

SMILE vs LASIK vs PRK vs ICL

SMILE is one of four refractive pathways at Eyeglow. The right choice depends on prescription, corneal anatomy and lifestyle:

AspectSMILELASIKPRKEVO ICL
Corneal flapNo — small 2–4 mm incision onlyYes (femto-cut flap, ~20 mm circumference)No — surface epithelium removedNo — corneal tissue preserved
Nerve transectionMinimal (small incision arc)Extensive (flap circumference)Surface onlyNone (intraocular)
Dry eye riskLower than LASIKModerateLower than LASIKMinimal
Recovery time1–3 days24–48 hours7–14 days24 hours
Suitable for thin corneaBetter than LASIKLimitedBest surface optionCornea-preserving
Prescription range–1 to –10 D myopia, astigmatism to –3 DUp to –10 D myopia, +6 D hyperopia, 6 D astigmatismSimilar to LASIK–3 to –20 D myopia (broader)
Athlete / military suitabilityPreferred (no flap)Often restrictedPreferredPreferred (reversible)
Pricing

SMILE pricing

All-inclusive Eyeglow package pricing. Your final, personalised quote is confirmed after imaging review — with no obligation.

Procedure Eyeglow price (all-inclusive)
SMILE Eye Surgery — both eyes, all-inclusivefrom €1,300
Package transparency

What's included in your SMILE package

Included in package

  • Pre-op imaging (Pentacam, pachymetry, wavefront, dry eye, tear film)
  • Surgeon-led consultation (our refractive surgical team)
  • ZEISS VisuMax femtosecond SMILE procedure (both eyes)
  • 5-star hotel — 3 nights
  • VIP airport transfers (return)
  • All post-op drops + aftercare kit
  • Day-1, day-7, 1m, 3m, 6m, 12m follow-up reviews
  • Refractive enhancement (surface PRK) within 12 months if needed — no extra surgical fee
  • Multilingual coordinator — 24/7
  • Complication insurance — covers eligible post-operative medical complications during the recovery period at our partner accredited hospital (issued in line with the Turkish Ministry of Health International Health Tourism Authority Certificate)

Paid separately

Items below are not part of the medical package — your coordinator helps you arrange them at no markup.

  • Flights to/from Istanbul
  • Personal expenses
  • Optional enhancement procedure beyond 12 months
  • Unrelated medical treatments
  • Travel insurance (flight cancellation, baggage, general trip cover) — separate from the medical complication policy above; your coordinator can recommend a provider at no markup
Our team

The surgeons who will care for you

Your procedure is carried out by our refractive surgical team at our partner accredited hospital in Istanbul. Their training and sub-specialty focus are shown below.

Medically reviewed by Assoc. Prof. Dr. Muhammet Derda Özer, FICO

Candidacy

Are you a candidate for SMILE?

You may be a good candidate if

  • You are over 18 with a stable prescription for at least one year.
  • Your myopia is between –1 and –10 dioptres, with or without astigmatism up to –3 D.
  • Your corneal thickness is sufficient (typically ≥500 µm) and topography is regular on Pentacam.
  • You have a flap-related concern (athlete, military, contact-sport occupation, eye-rubbing history) and want a flapless refractive option.
  • You have mild-to-moderate dry eye and want a refractive procedure that preserves more corneal nerves than LASIK.

A different pathway may be safer if

  • Hyperopia (long-sightedness) — SMILE is FDA-approved for myopia only; LASIK / PRK / ICL are the alternatives.
  • Cornea below the SMILE planning threshold — PRK or ICL considered.
  • Signs of keratoconus, forme fruste keratoconus or any progressive corneal ectasia — cross-linking comes first.
  • Severe untreated dry eye — needs management before any refractive surgery.
  • Pregnancy or breastfeeding — SMILE is postponed.

Disclaimer. Information on this page is consistent with FDA SMILE approvals (myopia September 2016; myopic astigmatism October 2018), American Academy of Ophthalmology (AAO) Refractive Surgery Preferred Practice Pattern, American Society of Cataract & Refractive Surgery (ASCRS) consensus, and ZEISS Meditec global SMILE registry. It is educational and not a clinical recommendation. The only reliable way to know whether SMILE is the right option for you is a surgeon-reviewed evaluation based on Pentacam topography, pachymetry, wavefront aberrometry and tear film evaluation.

Risks & outcomes

Realistic outcomes — the risks that actually matter

Every refractive procedure has measurable risks. We list them here in the same plain language our surgical team uses in your consultation:

Slower visual recovery than LASIK

A small subset of patients (~10–15%) have a slightly slower first-week visual recovery than LASIK — most reach driving vision by day 2 but full sharpness can take 1 to 2 weeks. This is the trade-off for preserving corneal biomechanical strength.

Lenticule retrieval difficulty

Very rare (<0.5%) with experienced surgeons and modern VisuMax software — manual separation of the lenticule is the most operator-dependent step in SMILE. If a fragment is retained, conversion to surface PRK or careful re-entry resolves the issue without compromising long-term outcome.

Residual refractive error

Approximately 3 percent of patients require an enhancement within the first 12 months. SMILE enhancement is performed as a surface PRK touch-up (not a second SMILE) — included in your package at no extra surgical fee within 12 months.

Dry eye and glare at night

Less frequent and milder than after LASIK because the corneal nerve transection is minimal. Most symptoms resolve within 3 months; persistent severe symptoms are rare.

FAQ

Frequently asked questions about SMILE eye surgery

What is SMILE eye surgery and how does it work?

SMILE — Small Incision Lenticule Extraction — is a flapless refractive procedure that uses the ZEISS VisuMax femtosecond laser to create a precisely shaped disc of tissue (a "lenticule") inside the cornea, which the surgeon then removes through a 2-to-4-millimetre side incision. Removing the lenticule changes the corneal curvature and corrects myopia and astigmatism. The procedure takes 10 to 12 minutes per eye under topical anaesthetic. SMILE has been FDA-approved for myopia since September 2016 and for myopic astigmatism since October 2018; it has been performed worldwide for over a decade with more than seven million procedures completed (ZEISS Meditec global registry).

What is SMILE Pro and how is it different from classic ReLEx SMILE?

SMILE Pro is the latest generation of the procedure, performed on the ZEISS VisuMax 800 platform (introduced 2022). The key advances are: (1) Laser pulse delivery in approximately 10 seconds per eye — about three times faster than VisuMax 500. (2) Cyclorotation compensation — automatic correction for any eye rotation between the upright pre-op measurement and the supine surgical position, which improves astigmatic correction accuracy. (3) Centration assist — a more precise pupil-tracked centration. Classic ReLEx SMILE on VisuMax 500 remains an excellent option with extensive long-term data; SMILE Pro is faster and slightly more precise for complex astigmatism.

SMILE vs LASIK — which is better for me?

They serve overlapping patient profiles but with different trade-offs. LASIK reshapes the cornea by lifting a flap and ablating stromal tissue underneath — fastest visual recovery (24–48 hours), but the flap creates a permanent biomechanical seam and transects more corneal nerves (higher dry eye risk). SMILE creates a small 2-to-4-mm incision only — preserves more corneal biomechanical strength, lower dry eye risk, preferred for contact-sport athletes, military and eye-rubbers. The trade-off is slightly slower visual recovery in some patients (1–2 weeks for full sharpness). Visual outcomes at one year are comparable in the overlapping prescription range. Our refractive surgical team recommends one or the other based on your imaging and lifestyle — not as a preference.

Does SMILE eye surgery hurt?

No injections; topical anaesthetic drops numb the eye completely. Most patients describe a sensation of pressure for about 25 seconds while the suction ring stabilises the eye for the laser pulse, plus mild pressure during lenticule separation — but no pain. Some grittiness, mild light sensitivity and slight discomfort are normal for 24 to 48 hours after surgery and settle with the prescribed drops. Day-1 comfort is generally rated higher with SMILE than with PRK or LASIK in patient-reported outcome studies.

Am I a candidate for SMILE?

You are typically a candidate if you are over 18 with a stable prescription, myopia between –1 and –10 D (with or without astigmatism up to –3 D), corneal thickness ≥500 µm and regular Pentacam topography. You are not a candidate if you have hyperopia (SMILE is FDA-approved for myopia only — LASIK or ICL are the hyperopia options), corneal thickness below the planning threshold, suspected keratoconus, severe untreated dry eye, or active corneal disease. Our refractive surgical team confirms candidacy after Pentacam, pachymetry, wavefront aberrometry and tear film evaluation.

How long does SMILE eye surgery last?

The structural change to your cornea from SMILE is permanent. Long-term follow-up studies from ZEISS and independent investigators (Sekundo et al. 6-year follow-up; Kim et al. 5-year multicentre series) show stability of refractive outcome and corneal biomechanics at 5+ years. Most patients enjoy stable corrected vision indefinitely — the only natural change is the development of presbyopia in your 40s (the age-related need for reading glasses), which affects everyone regardless of whether they had refractive surgery.

How much does SMILE eye surgery cost at Eyeglow?

Eyeglow Health SMILE packages start from €1,300 for both eyes, including pre-op imaging, hotel for 3 nights, VIP transfer, complication insurance and one year of structured follow-up. Your final, personalised quote is confirmed after imaging review — with no obligation. We use the same ZEISS VisuMax platform used in major international refractive centres.

Does insurance cover SMILE surgery?

In most countries no. SMILE — like LASIK and PRK — is classified as elective refractive surgery and is not covered by standard private health insurance plans in the US, UK, Germany and most of Europe. Some employer flexible-spending accounts (FSAs) or health savings accounts (HSAs) in the US can be used for SMILE. Eyeglow provides a written itemised invoice for FSA/HSA submission or insurance reimbursement attempts; reimbursement is at the insurer's discretion.

How soon can I drive, exercise and fly after SMILE?

Most patients see clearly enough to drive within 24 to 48 hours, but we recommend waiting until after the day-7 post-op review. Light exercise from day 3, gym and weight training from day 7, swimming from day 14 (water carries an infection risk during epithelial healing). Flying is safe from 48 hours after surgery; most international patients fly home on day three or four after the day-1 review.

Can SMILE correct astigmatism?

Yes — SMILE has been FDA-approved for myopic astigmatism since October 2018, treating cylinder up to –3 D. SMILE Pro on VisuMax 800 includes automatic cyclorotation compensation, which improves astigmatic correction accuracy by correcting for any eye rotation between the upright pre-op measurement and the supine surgical position. Astigmatism above –3 D may be better corrected with topography-guided LASIK or an ICL Toric variant — our refractive surgical team recommends the right approach based on your topography.

What are the realistic risks of SMILE eye surgery?

The risks that matter in practice are: (1) Slightly slower visual recovery than LASIK in 10–15% of patients (full sharpness can take 1–2 weeks). (2) Lenticule retrieval difficulty in <0.5% of experienced-surgeon cases. (3) Residual refractive error needing enhancement in approximately 3% — included as a surface PRK touch-up within 12 months at no extra surgical fee. (4) Dry eye and night glare — milder and shorter than after LASIK because corneal nerve transection is minimal. Severe complications (corneal ectasia, sight-threatening events) are exceptionally rare with proper screening (<0.1%) and below LASIK rates in published meta-analyses.

Why choose Eyeglow Health over marketplace agencies?

Marketplaces refer you to several clinics and earn a commission per referral — your file rotates between coordinators and your surgeon is whoever the partner clinic happens to assign on the day. SMILE is a precision femtosecond procedure where lenticule separation technique varies meaningfully between surgeons. At Eyeglow Health your case is reviewed by our own refractive surgical team before any quote is issued. You speak to one named coordinator from first message to your twelve-month follow-up. We are a specialist eye clinic with a dedicated refractive pathway — not a multi-procedure marketplace.
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