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Vitreoretinal · Retina Specialist · Eye treatments

Retinal Vitrectomy Surgery in Turkey — 25G / 27G Microincision PPV at Eyeglow Istanbul

Retina-specialist-led vitreoretinal surgery using the Alcon Constellation and DORC EVA microincision platforms for retinal detachment, macular hole, epiretinal membrane, vitreous haemorrhage and diabetic vitrectomy. Every case is reviewed by our retina surgical team and includes a written quote, complication insurance and a year of structured OCT follow-up.

Retinal vitrectomy at Eyeglow, Istanbul
Procedure time45–90 min per eye
AnaesthesiaTopical + sedation or block
Hospital stayDay case (overnight occasional)
Posturing0–7 days (case-dependent)
Time in Istanbul7–14 nights
Follow-up1 year structured
What it is

What is a retinal vitrectomy?

Pars plana vitrectomy (PPV) is a microsurgical procedure to remove the vitreous gel from inside the eye, repair the retina, and replace the vitreous with a saline solution, gas bubble or silicone oil. Modern 25-gauge / 27-gauge microincision vitrectomy uses three sub-millimetre trans-conjunctival ports and takes 45 to 90 minutes per eye under topical anaesthetic with sedation.

At Eyeglow Health in Istanbul, vitrectomy is performed with the Alcon Constellation Vision System and DORC EVA platforms — the same equipment used in major US, UK and European vitreoretinal centres. Treatment plans are tailored to the indication: retinal detachment, full-thickness macular hole, epiretinal membrane (macular pucker), non-clearing vitreous haemorrhage, proliferative diabetic retinopathy and vitreomacular traction each have different surgical techniques, tamponade choices and posturing schedules.

Vitrectomy is a high-acuity intraocular procedure and is not appropriate for everyone. Stable asymptomatic membranes, active ocular infection, severe medical comorbidity, or patients unable to maintain posturing all require a different approach. That assessment belongs to a vitreoretinal surgeon who has personally reviewed your macular OCT, wide-field fundus imaging and visual acuity history — not to a marketing brochure.

How it works

From first consultation to recovery at home

  1. 01

    Online retina review

    You share your most recent macular OCT, fundus photograph, fluorescein angiography (if available) and any prior retinal notes. Our retina surgical team reviews your case and confirms the indication (detachment, macular hole, epiretinal membrane, vitreous haemorrhage, diabetic retinopathy or vitreomacular traction) — and what positioning will be needed after surgery — before a quote is issued.

  2. 02

    Pre-operative imaging in Istanbul

    On day 1 we repeat macular OCT, wide-field fundus imaging, B-scan ultrasonography (if media are opaque), endothelial cell count and a complete dilated retinal examination. These confirm the exact pathology, the extent of any retinal break or membrane, and whether a gas tamponade or silicone oil will be needed at the end of surgery.

  3. 03

    Personalised surgical plan

    Our retina surgical team explains the surgery in plain language: which membrane will be peeled, whether endolaser will be applied, what tamponade (SF6, C3F8 or silicone oil) will be used, and the post-operative posturing schedule. You sign consent only after every question has been answered.

  4. 04

    Pars plana vitrectomy (45–90 minutes per eye)

    25G or 27G microincision vitrectomy — three sub-millimetre trans-conjunctival ports are placed through the pars plana, the vitreous gel is removed with the Constellation or EVA vitrectomy platform, the retina is repaired (ILM peel, ERM peel, endolaser to retinal breaks, drainage of subretinal fluid as needed), and the eye is filled with a gas bubble or silicone oil tamponade according to the indication. Performed under topical anaesthetic with sedation, or a peribulbar block.

  5. 05

    Day 1 and weekly reviews

    A clear protective shield is worn at night for the first 2 weeks. You return on day 1, day 7, day 14 and again before flying. If you have a gas tamponade you must remain face-down or in lateral positioning for the prescribed period (typically 3–7 days for macular hole, 1–3 days for retinal detachment) and you cannot fly until the gas bubble dissolves — usually 2 weeks for SF6 and 6 to 8 weeks for C3F8.

  6. 06

    One-year structured aftercare

    Scheduled OCT and fundus reviews at one, three, six and twelve months. Visual recovery continues throughout the first 6 to 12 months as the macula remodels. If silicone oil was used, removal is scheduled at 3 to 6 months as a second-stage procedure (priced separately). Your coordinator stays the same throughout.

Indications

Vitrectomy by indication — what is repaired and how

Vitrectomy is one operation with many indications. The surgical steps, tamponade choice and recovery profile depend on the specific pathology:

AspectRetinal detachmentMacular holeEpiretinal membraneVitreous haemorrhage / diabetic
IndicationRetinal detachment (rhegmatogenous, tractional, exudative)Full-thickness macular holeEpiretinal membrane / macular puckerVitreous haemorrhage, diabetic retinopathy, vitreomacular traction
Typical surgery time60–90 min45–60 min45–60 min45–90 min (depends on retinopathy severity)
ILM / ERM peelSometimesAlways (ILM peel)Always (ERM ± ILM)Variable
Tamponade usedSF6 gas, C3F8 gas, or silicone oilC3F8 gas (3–6 weeks)Air or no tamponadeUsually none; gas if peripheral break
Post-op posturing1–3 days3–7 days face-downNone routinelyNone routinely
Visual recovery (median)3–12 months3–6 months (90%+ closure rate)3–6 months (70–80% acuity gain)4–12 weeks once media clear
Pricing

Vitrectomy pricing

All-inclusive Eyeglow package pricing. Your final, personalised quote is confirmed after imaging review — with no obligation.

Procedure Eyeglow price (all-inclusive)
Retinal Vitrectomy Surgery (PPV) — per eye, all-inclusive€4,000 – €6,000
Package transparency

What's included in your vitrectomy package

Included in package

  • Pre-op imaging (macular OCT, wide-field fundus, B-scan, endothelial cell count, fluorescein angiography if needed)
  • Retina-specialist consultation + surgical plan review
  • 25G / 27G microincision pars plana vitrectomy (Constellation or EVA platform)
  • ILM / ERM peel as indicated, endolaser to retinal breaks, drainage of subretinal fluid
  • Tamponade — SF6 or C3F8 gas (silicone oil quoted separately if removal needed)
  • 5-star hotel — 7 nights (longer stays available for complex cases)
  • VIP airport transfers (return)
  • All post-op drops + aftercare kit + posturing equipment if required
  • Day-1, day-7, day-14, 1m, 3m, 6m, 12m follow-up with OCT and fundus review
  • Multilingual retina coordinator — 24/7
  • Complication insurance — covers eligible post-operative medical complications during the recovery period at our partner accredited hospital (issued in line with the Turkish Ministry of Health International Health Tourism Authority Certificate)

Paid separately

Items below are not part of the medical package — your coordinator helps you arrange them at no markup.

  • Flights to/from Istanbul
  • Personal expenses
  • Silicone oil removal — quoted separately as a second-stage procedure at 3 to 6 months
  • Cataract surgery — vitrectomy accelerates cataract development; ~50–80% of patients require subsequent cataract surgery within 12 to 24 months, quoted separately
  • Anti-VEGF intravitreal injections for ongoing diabetic or AMD management — billed per injection
  • Unrelated medical treatments
  • Travel insurance (flight cancellation, baggage, general trip cover) — separate from the medical complication policy above; your coordinator can recommend a provider at no markup
Our team

The surgeons who will care for you

Your procedure is carried out by our retina surgical team at our partner accredited hospital in Istanbul. Their training and sub-specialty focus are shown below.

Medically reviewed by Assoc. Prof. Dr. Muhammet Derda Özer, FICO

From our practice

Vitrectomy outcomes from our own cases

The images below are from vitreoretinal surgery cases managed by our retina team in Istanbul — documented before treatment and after surgical repair, alongside intra-operative clinical imaging. They are shared to illustrate the conditions our team treats, not as a guarantee of any individual outcome.

Vitreoretinal surgery managed by the Eyeglow Health retina team in Istanbul — before and after surgical repair
Retinal repair managed by the Eyeglow Health retina team in Istanbul — before and after vitrectomy

Clinical images are published with documented patient consent and are from procedures performed by our own retina team. Individual results vary with retinal condition and disease stage; these images do not represent a promised result for any patient.

Candidacy

Are you a candidate for vitrectomy?

You may be a good candidate if

  • You have a confirmed retinal detachment requiring repair (rhegmatogenous, tractional or exudative).
  • You have a full-thickness macular hole confirmed on OCT (stages 2–4) and want a single-stage surgical closure.
  • You have an epiretinal membrane (macular pucker) with measurable visual acuity loss or metamorphopsia distorting daily reading.
  • You have a non-clearing vitreous haemorrhage limiting your ability to drive or work after 2–3 months of observation.
  • You have proliferative diabetic retinopathy with vitreous haemorrhage or tractional retinal detachment requiring vitrectomy.
  • You can commit to the posturing schedule (typically 3–7 days face-down for macular hole) and to a 2 to 6-week non-flying period if gas tamponade is used.

A different pathway may be safer if

  • Active ocular infection (endophthalmitis, severe uveitis) — must be controlled medically before any surgical intervention.
  • Stable, asymptomatic epiretinal membrane with preserved acuity — observation is the appropriate plan.
  • Recent intravitreal anti-VEGF injection within 7 days (timing must be coordinated).
  • Significant medical comorbidity preventing safe sedation or block anaesthesia (assessed case-by-case).
  • Patients unable to maintain post-operative posturing (frailty, severe musculoskeletal disease) — alternative tamponade or staged approach assessed individually.

Disclaimer. Information on this page is consistent with American Academy of Ophthalmology (AAO) Retina & Vitreous Preferred Practice Pattern, American Society of Retina Specialists (ASRS) consensus, Royal College of Ophthalmologists (RCO) UK vitreoretinal audit, and FDA-approved 25G / 27G microincision platforms (Alcon Constellation, DORC EVA). It is educational and not a clinical recommendation. The only reliable way to know whether vitrectomy is the right option for your eye is a vitreoretinal-specialist evaluation based on macular OCT, fundus examination and visual acuity history.

Risks & outcomes

Realistic outcomes — the risks that actually matter

Every vitreoretinal procedure has measurable risks. We list them here in the same plain language our surgical team uses in your consultation:

Post-vitrectomy cataract

The most common late event after vitrectomy in patients with their natural lens. Approximately 50 to 80 percent of phakic patients develop a visually significant cataract within 12 to 24 months — independent of the vitrectomy result. Treated with routine cataract surgery (Smart Lens or monofocal IOL) when it becomes symptomatic.

Retinal redetachment

Around 5 to 10 percent of retinal detachments require a second surgery, typically because of proliferative vitreoretinopathy (PVR) — scar tissue contraction inside the eye. Anatomic success after second surgery exceeds 90 percent in published series.

Elevated intraocular pressure

Common in the first 1–2 weeks especially after gas tamponade; managed with topical medication. Persistent glaucoma is uncommon (<5%) and treated with standard glaucoma protocols.

Endophthalmitis (intraocular infection)

Rare — published incidence below 0.1% with 25G/27G microincision vitrectomy and modern aseptic technique. Detected on day-1 review and treated immediately with intravitreal antibiotics if it ever occurs.

FAQ

Frequently asked questions about retinal vitrectomy

What is a vitrectomy?

A vitrectomy is a microsurgical procedure to remove the vitreous gel from the back of the eye — the gel that fills the space between the natural lens and the retina. Modern pars plana vitrectomy (PPV) uses three sub-millimetre trans-conjunctival ports through the pars plana of the eye (a safe entry zone 3.5–4 mm behind the corneal limbus) to insert miniature instruments — an infusion line, an illumination probe and a vitrectomy cutter. Eyeglow performs vitrectomy with 25-gauge and 27-gauge microincision platforms (Alcon Constellation, DORC EVA) — the same systems used in major US and European vitreoretinal centres. The procedure takes 45 to 90 minutes per eye and is performed as a day case.

Why might I need a vitrectomy?

The most common indications are: (1) Retinal detachment — to relieve vitreous traction on a retinal tear, drain subretinal fluid and apply laser. (2) Full-thickness macular hole — to peel the internal limiting membrane (ILM) and place a gas tamponade allowing the hole to close. (3) Epiretinal membrane (macular pucker) — to peel the membrane and restore central vision. (4) Non-clearing vitreous haemorrhage — to remove blood obscuring the retina. (5) Proliferative diabetic retinopathy — to remove blood, relieve tractional detachment and apply panretinal laser. (6) Vitreomacular traction — to release the abnormal vitreous-macular adhesion when it threatens vision. Our retina surgical team confirms the exact indication after macular OCT and fundus examination.

Is a vitrectomy a serious operation?

Vitrectomy is a precise microsurgical procedure with a documented safety profile spanning more than three decades. Modern 25G and 27G microincision platforms have reduced surgical trauma significantly — most cases are now sutureless and day-case. American Society of Retina Specialists (ASRS) consensus reports anatomic success rates of 85 to 95 percent for primary retinal detachment, 90 to 95 percent macular hole closure, and 70 to 80 percent visual acuity improvement after ERM peel. Serious complications (endophthalmitis, severe vision loss) are rare (<1%). It is, however, intraocular surgery and not a procedure to take lightly — it should only be done when the visual benefit outweighs the surgical risk.

How long does vitrectomy surgery take?

Most vitrectomies take 45 to 90 minutes per eye. Macular hole or simple epiretinal membrane: typically 45 to 60 minutes. Retinal detachment repair: 60 to 90 minutes. Complex diabetic tractional detachment: 90 to 120+ minutes. Both eyes are not operated on the same day — the second eye, if needed, is scheduled at least 2 to 4 weeks later to allow the first eye to settle and to monitor visual recovery before exposing the fellow eye to surgical risk.

How many days face-down after vitrectomy?

The posturing requirement depends on what was done and what tamponade was placed: (1) Macular hole with C3F8 gas — typically 3 to 7 days face-down or strict prone positioning to keep the gas bubble pressing against the hole. (2) Retinal detachment with SF6 or C3F8 — 1 to 3 days head-down or lateral positioning according to the break location. (3) Epiretinal membrane peel without tamponade — no positioning needed. (4) Silicone oil tamponade — no strict positioning, but avoid lying flat on your back for 1 week. Our retina surgical team gives you a written positioning schedule before surgery and we provide face-down rental equipment (massage table, mirror) for complex cases.

What can I not do after a vitrectomy?

For the first 2 weeks: do not rub the eye, do not let water enter the eye (no swimming, careful in the shower), do not lift heavy weights or do strenuous exercise, do not drive until the day-7 review and a vision check. If you have a gas tamponade: do not fly until the bubble has dissolved (typically 2 weeks for SF6, 6 to 8 weeks for C3F8), and warn any anaesthetist about your gas bubble before any unrelated surgery — nitrous oxide can expand the bubble dangerously. After 2 weeks the eye is robust enough for normal activity, although vision continues to improve over the next 3 to 6 months.

How soon can I fly after vitrectomy?

If gas tamponade was used, you cannot fly until the gas bubble has fully dissolved — confirmed at the post-operative review. SF6 (sulphur hexafluoride) dissolves in approximately 2 weeks; C3F8 (perfluoropropane) dissolves in 6 to 8 weeks. Air-only fills dissolve within 5 to 7 days. Silicone oil tamponade has no flight restriction. Flying with residual gas is dangerous — atmospheric pressure changes expand the gas, raising intraocular pressure to vision-threatening levels. Eyeglow plans your travel dates around your tamponade choice so you do not arrive home stranded.

How much does retinal vitrectomy surgery cost at Eyeglow?

Eyeglow Health all-inclusive packages for retinal vitrectomy surgery are €4,000 – €6,000 per eye, including pre-op imaging, hotel for 7 nights, VIP transfer, complication insurance and one year of structured OCT follow-up. Your final, personalised quote is confirmed after imaging review — with no obligation.

Will I need cataract surgery after vitrectomy?

Yes — almost certainly within 12 to 24 months if you are phakic (still have your natural lens) at the time of vitrectomy. The published rate is 50 to 80 percent across vitreoretinal surgery series. Removing the vitreous changes the oxygen environment around the natural lens, accelerating nuclear sclerosis. The cataract that develops is usually a posterior subcapsular or nuclear cataract — well managed with routine phacoemulsification and an IOL implant. Some surgeons offer a combined "phaco-vitrectomy" in the same session for patients with co-existing cataract; our retina surgical team discusses this option case-by-case. Cataract surgery is not included in the vitrectomy package and is quoted separately.

Are you awake during a vitrectomy?

Most vitrectomies are performed under topical anaesthetic with intravenous sedation, or under a peribulbar / sub-Tenon block — you are awake but the eye is fully numb and you feel no pain. Many patients describe seeing colours, lights and movement during the procedure but no sharp images. General anaesthesia is reserved for patients who specifically request it, for children, or for very complex cases. The choice of anaesthesia is discussed with our anaesthetist before surgery and tailored to your medical history.

What are the realistic risks of vitrectomy?

The risks that matter in practice are: (1) Post-vitrectomy cataract — 50 to 80 percent of phakic patients within 12 to 24 months (essentially expected). (2) Retinal redetachment — 5 to 10 percent of detachment cases require second surgery, usually for proliferative vitreoretinopathy. (3) Elevated intraocular pressure — common in first 1–2 weeks especially after gas; managed with drops. (4) Endophthalmitis (intraocular infection) — rare (<0.1%) with modern 25G/27G technique. Severe permanent vision loss is uncommon when vitrectomy is performed for an appropriate indication. These figures are consistent with American Society of Retina Specialists (ASRS) and Royal College of Ophthalmologists (RCO) UK vitreoretinal audit data.

Why choose Eyeglow Health for retinal surgery over marketplace agencies?

Marketplaces refer you to several clinics and earn a commission per referral — for high-acuity retinal surgery your file rotates between coordinators and your surgeon is whoever the partner clinic happens to assign on the day. Retinal surgery is the highest-stakes ocular procedure — outcomes depend more on the named surgeon than on the platform. At Eyeglow Health your case is reviewed by our own vitreoretinal surgical team. You speak to one named coordinator from first message to your twelve-month OCT follow-up. We are a specialist eye clinic with a dedicated vitreoretinal pathway — not a multi-procedure marketplace.
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